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Henry Pestov
Henry Pestov


Health equity has long been the dominant theme in the work of the Aetna Foundation. Recent data have focused on disparities through another lens, particularly the correlation between where people live (i.e., ZIP code) and their quality-and length-of life. In various cities across America, average life expectancies in certain communities are 20-30 years shorter than those mere miles away. In general, health disparities are founded on a complex interplay of racial, economic, educational, and other social factors. For example, breastfeeding rates in the United States differ significantly depending upon the race and income of the mother. Government policy makers are acutely aware of these disparities, but recent health system reforms have focused predominately on the processes used to administer, finance, and deliver care. What is needed is an approach that considers the health and wellness of all people in a geographic area, beyond established patients, and that measures more than clinical factors-such as genetics, environmental health, social circumstances, and individual behaviors. Solutions also must extend beyond the traditional healthcare arena. In particular, novel technological innovations show promise to bridge gaps between our healthcare capabilities and the needs of underserved populations. Digital tools are poised to revolutionize measurement, diagnostics, treatment, and global aspect of our healthcare system. The Aetna Foundation views technology as a core strategy in reducing health inequities through an approach that addresses both clinical and social factors in populations to dismantle the persistent paradigm of ZIP code as personal health destiny.


An Authorization differs from an informed consent in that an Authorization focuses on privacy risks and states how, why, and to whom the PHI will be used and/or disclosed for research. An informed consent, on the other hand, provides research subjects with a description of the study and of its anticipated risks and/or benefits, and a description of how the confidentiality of records will be protected, among other things. An Authorization can be combined with an informed consent document or other permission to participate in research. Whether combined with an informed consent or separate, an Authorization must contain the following specific core elements and required statements stipulated in the Rule:

The Privacy Rule does not specify who may draft the Authorization, so a researcher could draft it regardless of whether the researcher is a covered entity. However, in order to have a Privacy Rule-compliant Authorization, it must be written in plain language and contain the core elements and required statements, and a signed copy must be provided to the individual signing it if the covered entity itself is seeking the Authorization. The companion piece Sample Authorization Language contains language that illustrates the inclusion of core elements and required statements.

This, however, is only a start. Advocating for nutritious eating makes a scant difference in a food desert. Praising the benefits of physical exercise helps little when jogging in a nearby neighborhood could cost your life. And warnings about the dangers of drug and alcohol abuse will hardly be heard in areas devoid of opportunity and hope. These challenges will not be solved by medicine alone. As a society, we have been shaken to our core by the recent injustices we have witnessed; we cannot look away. We must confront and address through policy the systemic inequities that have turned our zip codes into such powerful predictors of human health.

Finally, though you might not think of them as core muscles, the tiny muscles that fine-tune the movements of your vertebrae make up the deepest layer. The powerful river of the psoas flows right alongside these muscles.

Therein lies the danger of many core workouts: If your transverse abdominis is weak, your psoas will pull too strongly on your spine. A prime example of the danger comes from doing exercises such as leg lifts. The transverse abdominis should do the job of holding your spine steady while your psoas and thigh muscles lift and lower your legs. Your effort to maintain a neutral curve in your spine throughout the exercise is what gives your abdominals a workout. Your transverse abdominis tightens to prevent your psoas from pulling your back into an exaggerated arch as you lift and lower your legs.

But the exercise essentially pits your core muscles and psoas against each other. The problem is that your core is most often no match for the combined power of your psoas and gravity. The end result is that tremendous pressure is placed on your lumbar spine, which causes your low back to overarch and can lead to low-back pain or even to injury.

By locating the action of the transverse abdominis in the following exercise, you can experience the support it gives to your spine and the release it provides your psoas, and apply that understanding to any core work you do.

A vulnerability rated with a Critical impact is one which could potentially be exploited bya remote attacker to get Log4j to execute arbitrary code (either as the user the server isrunning as, or root). These are the sorts of vulnerabilities that could be exploited automaticallyby worms. Critical vulnerabilities score between 9.0 and 10.0 on theCVSS v3 calculator.

A vulnerability rated as High impact is one which could result in the compromise of dataor availability of the server. For Log4j this includes issues that allow an easy remote denialof service (something that is out of proportion to the attack or with a lasting consequence),access to arbitrary files outside of the context root, or access to files that should be otherwiseprevented by limits or authentication. High vulnerabilities score between 7.0 and 8.9 on theCVSS v3 calculator.

A vulnerability is likely to be rated as Moderate if there is significant mitigation to make theissue less of an impact. This might be because the flaw does not affect likely configurations, orit is a configuration that isn't widely used. Moderate vulnerabilities score between 4.0 and 6.9 on theCVSS v3 calculator.

All other security flaws are classed as a Low impact. This rating is used for issues that are believedto be extremely hard to exploit, or where an exploit gives minimal consequences. Low vulnerabilitiesscore between 0.1 and 3.9 on the CVSS v3 calculator.

By default, pigz uses the number of available cores, or eight if it could not query that. You can ask for more with -p n, e.g. -p 32. pigz has the same options as gzip, so you can request better compression with -9. E.g.

Regarding multithreaded XZ support. If you are running version 5.2.0 or above of XZ Utils, you can utilize multiple cores for compression by setting -T or --threads to an appropriate value via the environmental variable XZ_DEFAULTS (e.g. XZ_DEFAULTS="-T 0").

Use as many parameters as you want.In this case -9 is the compression level and -p 4 is the number of cores dedicated to compression.If you run this on a heavy loaded webserver, you probably don't want to use all available cores.

A relatively newer (de)compression tool you might want to consider is zstandard. It does an excellent job of utilizing spare cores, and it has made some great trade-offs when it comes to compression ratio vs. (de)compression time. It is also highly tweak-able depending on your compression ratio needs.

WARNING: The upgrade process will affect all files and folders included in the main WordPress installation. This includes all the core files used to run WordPress. If you have made any modifications to those files, your changes will be lost.

As part of its focus on core assets, Zip said it would close its Zip Business unit and exit the Trade and Trade Plus product suite, and withdraw from Singapore by the end of September to reduce cash burn.

Compared to the Core i5-12600K, the four E-cores are gone, the L3 cache is reduced from 20 MB to 18 MB, the turbo clock speed has been wound down by 10%, and the base power has been slashed from 125 watts to just 65 watts. That doesn't sound so appealing... but what makes the i5-12400 so exciting is the price.

What you're getting for around $200 is a 6 P-core, 12-thread Alder Lake CPU that operates up to 4.4 GHz with an 18 MB L3 cache and UHD 730 graphics. So it should be even faster than last generation's Core i5-11600K, which came in at $270 a year ago.

Starting with the Cinebench R23 multi-core results, we find that the 12400 is good for just over 12,000 points, and when following the 65-watt spec, it was just 3% slower. That being the case, it's incredible to see the base-spec 12400 beating the 11600K by an 8% margin and the 10600K by a massive 32%.

Perhaps most impressive of all is the 9% margin it defeated the 5600X by, which doesn't bode particularly well for AMD. Finally when compared to the 12600K, the 12400 was 30% slower and this is partly due to the 10% reduction in frequency along with the removal of the 4 E-cores and a 10% reduction in L3 cache capacity.

Adobe Photoshop isn't a core-heavy application, so both i5-12400 configurations delivered virtually the same result. That means no matter which way you slice it, the locked Core i5 is as powerful as the Ryzen 5 5600X. The 12600K, on the other hand, is clocked 11% higher and consequently was 11% faster in this test.

Because this game only uses a single core heavily, the power configuration doesn't matter, allowing the 12400 to produce a score of 202 pts even when adhering to the 65-watt spec. That's the same score you'll receive from a Zen 3 processor and only 2.5% less than the 12600K. 041b061a72


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